ДО ПИТАННЯ ПРО ТОКСИЧНІСТЬ ДИМЕТИЛСУЛЬФОКСИДУ ДЛЯ КЛІТИН ССАВЦІВ ТА РЕАКЦІЇ КЛІТИН НА НЬОГО
DOI:
https://doi.org/10.15407/exp-oncology.2024.02.174Ключові слова:
диметилсульфоксид, клітини ссавців, цитотоксичні ефекти, біологічні зміни, молекулярні зміни, реакції клітинАнотація
Диметилсульфоксид (ДМСО) є загальноприйнятним розчинником для нерозчинних у воді речовин та ліків при проведенні медичних та біологічних досліджень. Однак ДМСО спричинює різноманітний вплив на клітини, що виявлено в багатьох дослідженнях in vitro. Біологічні ефекти ДМСО в нормальних та трансформованих клітинах стисло розглянуто в статті.
Посилання
Notman R, Noro M, O’Malley B, Anwar J. Molecular basis for dimethylsulfoxide (DMSO) action on lipid mem- branes. J Am Chem Soc. 2006;128(43):13982-13983. https://doi.org/10.1021/ja063363t
Capriotti K, Capriotti JA. Dimethyl sulfoxide: history, chemistry, and clinical utility in dermatology. J Clin Aesthet Dermatol. 2012;5(9):24-26. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460663
Da Violante G, Zerrouk N, Richard I, et al. Evaluation of the cytotoxicity effect of dimethyl sulfoxide (DMSO) on Caco2/TC7 colon tumor cell cultures. Biol Pharm Bull. 2002;25(12):1600-1603. https://doi.org/10.1248/ bpb.25.1600
de Abreu Costa L, Henrique Fernandes Ottoni M, dos Santos M, et al. Dimethyl sulfoxide (DMSO) decreases cell proliferation and TNF-α, IFN-γ, and IL-2 cytokines production in cultures of peripheral blood lymphocytes. Mol- ecules. 2017;22(11):1789. https://doi.org/10.3390/molecules22111789
Dludla PV, Jack B, Viraragavan A, et al. A dose-dependent effect of dimethyl sulfoxide on lipid content, cell vi- ability and oxidative stress in 3T3-L1 adipocytes. Toxicol Rep. 2018;5:1014-1020. https://doi.org/10.1016/j. toxrep.2018.10.002
Moskot M, Jakóbkiewicz-Banecka J, Kloska A, et al. The role of dimethyl sulfoxide (DMSO) in gene expression modulation and glycosaminoglycan metabolism in lysosomal storage disorders on an example of mucopolysacchari- dosis. Int J Mol Sci. 2019;20(2):304. https://doi.org/10.3390/ijms20020304
Pal R, Mamidi MK, Das AK, Bhonde R. Diverse effects of dimethyl sulfoxide (DMSO) on the differentiation poten- tial of human embryonic stem cells. Arch Toxicol. 2012;86:651-661. https://doi.org/10.1007/s00204-011-0782-2
Singh M, McKenzie K, Ma X. Effect of dimethyl sulfoxide on in vitro proliferation of skin fibroblast cells. J Biotech Res. 2017;8:78-82. https://www.btsjournals.com/volume-8
Tamagnini F, Scullion S, Brown JT, Randall AD. Low concentrations of the solvent dimethyl sulphoxide alter in- trinsic excitability properties of cortical and hippocampal pyramidal cells. PLoS One. 2014;9(3):e92557. https://doi. org/10.1371/journal.pone.0092557
Wang C-C, Lin S-Y, Lai Y-H, et al. Dimethyl sulfoxide promotes the multiple functions of the tumor suppressor HLJ1 through activator protein-1 activation in NSCLC cells. PLoS One. 2012;7(4):e33772. https://doi.org/10.1371/journal. pone.0033772
Yi X, Liu M, Luo Q, et al. Toxic effects of dimethyl sulfoxide on red blood cells, platelets, and vascular endothelial cells in vitro. FEBS Open Bio. 2017;7(4):485-494. https://doi.org/10.1002/2211-5463.12193
Yuan C, Gao J, Guo J, et al. Dimethyl sulfoxide damages mitochondrial integrity and membrane potential in cultured astrocytes. PLoS One. 2014;9(9):e107447. https://doi.org/10.1371/journal.pone.0107447
Herbener VJ, Burster T, Goreth A, et al. Considering the Experimental Use of Temozolomide in Glioblastoma Re- search. Biomedicines. 2020;8(6):151. https://doi.org/10.3390/biomedicines8060151
Kloverpris H, Fomsgaard A, Handley A, et al. Dimethyl sulfoxide (DMSO) exposure to human peripheral blood mononuclear cells (PBMCs) abolish T cell responses only in high concentrations and following coincubation for more than two hours. J Immunol Methods. 2010;356(1-2):70-78. https://doi.org/10.1016/j.jim.2010.01.014
Hajighasemi F, Tajic S. Assessment of cytotoxicity of dimethyl sulfoxide in human hematopoietic tumor cell lines.
Iran J Blood Cancer. 2017;9(2):48-53. http://ijbc.ir/article-1-719
Jamalzadeh L, Ghafoori H, Sariri R, et al. Cytotoxic effects of some common organic solvents on MCF-7, RAW-
7 and human umbilical vein endothelial cells. Avicenna J Med Biochem. 2016;4(1):e33453. https://www.sid.ir/ paper/343031
Kuroda K, Komori T, Ishibashi K, et al. Non-aqueous, zwitterionic solvent as an alternative for dimethyl sulfoxide in the life sciences. Commun Chem. 2020;3:163. https://doi.org/10.1038/s42004-020-00409-7
Verheijen M, Lienhard M, Schrooders Y, et al. DMSO induces drastic changes in human cellular processes and epi- genetic landscape in vitro. Sci Rep. 2019;9:4641. https://doi.org/10.1038/s41598-019-40660-0
Hall MD, Telma KA, Chang K-E, et al. Say no to DMSO: dimethylsulfoxide inactivates cisplatin, carboplatin, and other platinum complexes. Cancer Res. 2014;74(14):3913-3922. https://doi.org/10.1158/0008-5472.CAN-14-0247
Raghavan R, Cheriyamundath S, Madassery J. Dimethyl sulfoxide inactivates the anticancer effect of cisplatin against human myelogenous leukemia cell lines in in vitro assays. Indian J Pharmacol. 2015;47(3):322-324. https://doi. org/10.4103/0253-7613.157132
Fischer SJ, Benson LM, Fauq A, et al. Cisplatin and dimethyl sulfoxide react to form an adducted compound with reduced cytotoxicity and neurotoxicity. Neurotoxicology. 2008;29(3):444-452. https://doi.org/10.1016/j.neu- ro.2008.02.010
Uribe PM, Mueller MA, Gleichman JS, et al. Dimethyl sulfoxide (DMSO) exacerbates cisplatin-induced sensory hair cell death in zebrafish (Danio rerio). PLoS One. 2013;8(2):e55359. https://doi.org/10.1371/journal.pone.0055359
##submission.downloads##
Опубліковано
Як цитувати
Номер
Розділ
Ліцензія
Авторське право (c) 2024 Експериментальна онкологія
Ця робота ліцензується відповідно до Creative Commons Attribution-NonCommercial 4.0 International License.
