NON-STANDARD STRATEGIES IN THE TREATMENT OF ADVANCED CERVICAL CANCER: A CASE SERIES

Authors

  • V. Svintsitsky State Non-commercial Enterprise “National Cancer Institute”, Kyiv, Ukraine
  • M. Yegorov State Non-commercial Enterprise “National Cancer Institute”, Kyiv, Ukraine
  • E. Stakhovsky State Non-commercial Enterprise “National Cancer Institute”, Kyiv, Ukraine
  • Yu. Vitruk State Non-commercial Enterprise “National Cancer Institute”, Kyiv, Ukraine
  • O. Renkas State Non-commercial Enterprise “National Cancer Institute”, Kyiv, Ukraine
  • A. Svintsitska State Non-commercial Enterprise “National Cancer Institute”, Kyiv, Ukraine
  • O. Bakai State Non-commercial Enterprise “National Cancer Institute”, Kyiv, Ukraine
  • L. Taran State Non-commercial Enterprise “National Cancer Institute”, Kyiv, Ukraine
  • N. Bankovska State Non-commercial Enterprise “National Cancer Institute”, Kyiv, Ukraine

DOI:

https://doi.org/10.15407/exp-oncology.2025.04.467

Keywords:

advanced cervical cancer, radical surgical treatment, symptomatic retroperitoneal lymphocyst, pelvic exenteration

Abstract

Background. Cervical cancer (СС) continues to be the leading cancer pathology affecting women of both young and older ages. In the advanced stages of СС, the choice of treatment typically favors chemoradiotherapy. However, in a number of cases, radical surgery may be the only effective treatment. Th s issue requires further analysis. Materials and Methods. Five selected cases of the advanced СС (stages IIa—IVa) that required non-standard treatment are presented. Results. In all presented cases, the radical surgical treatment had an undeniable immediate curative effect. On follow-up, two patients are alive without any evidence of the disease; two patients died from disease progression and one patient is still receiving treatment for bone recurrence. Conclusions. Despite the fact that in most cases of advanced stages of СС, chemoradiotherapy is effectively used, in some selected cases, surgery may be leading and effective if the operation is performed in a radical manner. Important in this regard are the clinical experience, high level of surgical skills, presence of a multidisciplinary team, and the technical equipment of the medical center for performing such operations.

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Published

05.03.2026

How to Cite

Svintsitsky, V., Yegorov, M., Stakhovsky, E., Vitruk, Y., Renkas, O., Svintsitska, A., … Bankovska, N. (2026). NON-STANDARD STRATEGIES IN THE TREATMENT OF ADVANCED CERVICAL CANCER: A CASE SERIES. Experimental Oncology, 47(4), 467–477. https://doi.org/10.15407/exp-oncology.2025.04.467

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