INFRARED THERMAL IMAGING CONTROL OF RADIATION DERMATITIS DYNAMICS

Authors

  • L. Miroshnichenko State Institution «Grigoriev Institute for Medical Radiology and Oncology of the National Academy of Medical Sciences of Ukraine», Kharkiv, Ukraine
  • L. Vasiliev State Institution «Grigoriev Institute for Medical Radiology and Oncology of the National Academy of Medical Sciences of Ukraine», Kharkiv, Ukraine
  • G. Shustakova B. Verkin Institute for Low Temperature Physics and Engineering of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine
  • E. Gordiyenko B. Verkin Institute for Low Temperature Physics and Engineering of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine
  • Yu. Fomenko B. Verkin Institute for Low Temperature Physics and Engineering of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine
  • I. Dunaieva Kharkiv National Medical University, Kharkiv, Ukraine

DOI:

https://doi.org/10.15407/exp-oncology.2023.04.493

Keywords:

oncology, radiation therapy, dermatitis, thermography

Abstract

Background. Radiation-induced dermatitis impairs the quality of life of cancer patients and may lead to the need of interrupting radiotherapy. The grade of dermatitis is subjectively assessed by the visual examination. There is an urgent need for both objective and quantitative methods for assessing the current grade of dermatitis and predicting its severity at an early stage of radiotherapy. Aim. The aim of the study was to evaluate the advantages and limitations of infrared thermography for monitoring the current level of radiation-induced dermatitis and predicting its severity by quantitative analysis of the thermal field dynamics in the irradiated zone. Materials and Methods. 30 adult patients were examined by infrared thermography during the course of 2D conventional radiotherapy for malignant tumors of various types and localizations. Our approach for quantifying the thermal field caused by dermatitis alone was applied. A statistical (correlation and ROC) analysis was performed. Results. Dermatitis of varying severity was observed in 100% of the patients studied. The dynamics in the intensity of the anomalous thermal fields in the irradiated zone correlated with the dynamics of dermatitis grades, excluding the case of a radiosensitive tumor (correlation coefficient 0.74÷0.84). It was found that the maximum toxicity (dermatitis grade ≥ 3) develops in patients who how significant hyperthermia in the area of interest (≥ 0.7 °C) at an early stage of radiotherapy. The ROC analysis demonstrated the "good quality" of the prognosis method (AUC = 0.871). Conclusions. The non-invasive and cheap infrared thermography is a suitable tool for objective quantitative monitoring the current dermatitis grade during radiotherapy as well as predicting its severity for any tumor location.

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Published

03.02.2024

How to Cite

Miroshnichenko, L., Vasiliev, L., Shustakova, G., Gordiyenko, E., Fomenko, Y., & Dunaieva, I. (2024). INFRARED THERMAL IMAGING CONTROL OF RADIATION DERMATITIS DYNAMICS. Experimental Oncology, 45(4), 493–503. https://doi.org/10.15407/exp-oncology.2023.04.493

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