Scrotal cutaneous metastasis from rectal squamous cell carcinoma: a rare evolution into a rare tumor

Authors

  • V. De Giorgi Section of Dermatology, Department of Health Sciences, University of Florence, Florence 50124, Italy
  • F. Venturi 1Section of Dermatology, Department of Health Sciences, University of Florence, Florence 50124, Italy
  • F. Portelli 1Section of Dermatology, Department of Health Sciences, University of Florence, Florence 50124, Italy
  • P. Maida Clinica Luganese Moncucco, Lugano 6900, Switzerland
  • F. Scarfì Section of Dermatology, Department of Health Sciences, University of Florence, Florence 50124, Italy
  • L. Trane Section of Dermatology, Department of Health Sciences, University of Florence, Florence 50124, Italy
  • A. Gori Cancer Research “AttiliaPofferi” Foundation, Pistoia 51100, Italy
  • F. Silvestri Section of Dermatology, Department of Health Sciences, University of Florence, Florence 50124, Italy
  • D. Massi Section of Pathology, Department of Health Sciences, University of Florence and Histopathology and Molecular Diagnostics, Careggi University Hospital, Florence 50124, Italy

DOI:

https://doi.org/10.32471/exp-oncology.2312-8852.vol-43-no-2.16284

Keywords:

cutaneous metastasis, dermoscopy, squamous cell carcinoma

Abstract

Summary. The scrotum is a rare site for metastases and represents less than 1% of the body’s total surface area. Clinically, metastatic deposits in the scrotum can present in a variety of ways. They may appear as solitary cutaneous nodules, papules, plaques, or generalized induration or edema. Indeed, scrotum metastasis may be mistaken for other skin lesions since several dermatologic conditions can present with inflammation or dermatitis of the scrotum. Properly diagnosing cutaneous metastasis requires histopathological examination since the clinical appearances are, as described, highly variable and non-specific. We present a 63-year-old man with painless nodules on the scrotal skin. Excisional biopsy of the nodules revealed a metastasis from rectal squamous cell carcinoma. The incidence of this kind of tumors is estimated around 0.1–0.25 per 1000 colorectal neoplasms.

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Published

26.05.2023

How to Cite

Giorgi, V. D., Venturi, F., Portelli, F., Maida, P., Scarfì, F., Trane, L., … Massi, D. (2023). Scrotal cutaneous metastasis from rectal squamous cell carcinoma: a rare evolution into a rare tumor. Experimental Oncology, 43(2), 177–179. https://doi.org/10.32471/exp-oncology.2312-8852.vol-43-no-2.16284