Clinicomorphological observation of refractory hepatoblastoma: a case report

Authors

  • B.M. Filenko Ukrainian Medical Stomatological Academy, Poltava 36011, Ukraine
  • I.I. Starchenko Ukrainian Medical Stomatological Academy, Poltava 36011, Ukraine
  • N.V. Royko Ukrainian Medical Stomatological Academy, Poltava 36011, Ukraine
  • N.I. Vynnyk Ukrainian Medical Stomatological Academy, Poltava 36011, Ukraine
  • L.V. Dyachenko Poltava Regional Pathoanatomical Bureau, Poltava 36011, Ukraine

DOI:

https://doi.org/10.32471/exp-oncology.2312-8852.vol-42-no-3.14855

Keywords:

CD10, hepatoblastoma, immunohistochemical characteristics, prognostic factors

Abstract

Summary. The clinical case of refractory hepatoblastoma with lethal outcome followed by pathomorphological verification has been analyzed. The true causes of hepatoblastoma development remain unknown. The prognostic factors of the disease require detailed study in complex investigations that would include histological, clinical, laboratory, and immunohistochemical characteristics. However, comparing clinical and histopathological parameters with CD10 expression could have a diagnostic role and may be useful in understanding tumorigenesis and prognostic analysis of a given tumor.

References

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Koh KN, Park M, Kim BE, et al. Prognostic implications of serum alpha-fetoprotein response during treatment of hepatoblastoma. Pediatr Blood Cancer 2011; 57: 554–60.

Kiruthiga KG, Banumathi R, Soumitra S, et al. Histological and immunohistochemical study of hepatoblastoma: correlation with tumour behaviour and survival. J Gastrointest Oncol 2018; 9: 326–37.

Zhang Q, Ming J, Zhang S, et al. A rare case of adult hepatoblastoma with neuroendocrine differentiation misdiagnosed as neuroendocrine tumor. Int J Clin Exp Pathol 2013; 6: 308–13.

Mishra D, Sunita S, Narayan G. Role of B cell development marker CD10 in cancer progression and prognosis. Mol Biol Int 2016; 2016: 4328697.

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Published

31.05.2023

How to Cite

Filenko, B., Starchenko, I., Royko, N., Vynnyk, N., & Dyachenko, L. (2023). Clinicomorphological observation of refractory hepatoblastoma: a case report. Experimental Oncology, 42(3), 245–247. https://doi.org/10.32471/exp-oncology.2312-8852.vol-42-no-3.14855

Issue

Vol. 42 No. 3 (2020): Experimental Oncology

Section

Case report

License

Copyright (c) 2023 Experimental Oncology

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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