Thyroid metastasis of vaginal leiomyosarcoma: a case report and review of the literature
DOI:
https://doi.org/10.32471/exp-oncology.2312-8852.vol-42-no-3.15029Keywords:
metastatic thyroid carcinoma, vaginal leiomyosarcomaAbstract
Summary. Metastasis of vaginal leiomyosarcoma to the thyroid gland is an extremely rare event. Here, we report a case of thyroid metastasis of vaginal leiomyosarcoma. A 65-year-old female patient presented with a multinodular toxic goiter. 5 years earlier the patient has undergone a radical vaginal resection followed by chemotherapy due to high-grade vaginal leiomyosarcoma. Fine-needle aspiration cytology of the right thyroid lobe was suggestive of the benign thyroid lesion. As the diagnosis was not clear, following a multidisciplinary team discussion the decision was made to proceed with a total thyroidectomy. Pathologic assessment of the tumor confirmed thyroid metastasis of vaginal leiomyosarcoma.
References
Siegel RL, Miller KD, Jemal A. Cancer statistics. CA Cancer J Clin 2016; 66: 7–30.
Zheng X, Rongyao Z, Jing L. A large primary retroperitoneal vaginal leiomyosarcoma: a case report. J Med Case Rep 2015; 9: 130.
Khosla D, Patel FD, Kumar R, et al. Leiomyosarcoma of the vagina: a rare entity with comprehensive review of the literature. Int J Appl Basic Med Res 2014; 4: 128–30.
Suh MJ, Park DC. Leiomyosarcoma of the vagina: a case report and review from the literature. J Gynecol Oncol 2008; 19: 261–4.
Gong L, Liu H, Yang KX, et al. Stage IV primary vaginal leiomyosarcoma with lung and breast metastases. Breast Care (Basel) 2012; 7: 150–2.
Hegerova L, Griebeler ML, Reynolds JP, et al. Metastasis to the thyroid gland: report of a large series from the Mayo Clinic. Am J Clin Oncol 2015; 38: 338–42.
Tsai HJ, Ruan CW, Kok VC, et al. A large primary vaginal leiomyosarcoma diagnosed postoperatively and uterine leiomyomas treated with surgery and chemotherapy. J Obstet Gynaecol 2013; 33: 643–4.
Kumar V, Abbas AK, Fausto N, Aster J. Robbins and Cotran Pathologic Basis of Disease. Philadelphia: Saunders Elsevier, USA, 2010. 1464 р.
Keller N, Godoy H. Leiomyosarcoma of the vagina: an exceedingly rare diagnosis. Case Rep Obstet Gynecol 2015; 2015: 363895.
Gadducci A, Cosio S, Romanini A, et al. The management of patients with uterine sarcoma: a debated clinical challenge. Crit Rev Oncol Hematol 2008; 65: 129–42
Nixon IJ, Coca-Pelaz A, Kaleva AI, et al. Metastasis to the thyroid gland: a critical review. Ann Surg Oncol 2017; 24: 1533–9.
Umeadi UP, Ahmed AS, Slade RJ, et al. Vaginal leiomyosarcoma. J Obstet Gynaecol 2008; 28: 553–4.
Yang S, Park K, Kim J. Thyroid metastasis from breast carcinoma accompanied by papillary thyroid carcinoma. Case Rep Oncol 2014; 7: 528–33.
Papi G, Fadda G, Corsello SM, et al. Metastases to the thyroid gland: prevalence, clinicopathological aspects and prognosis: a 10-year experience. Clin Endocrinol (Oxf) 2007; 66: 565–71.
Diaconescu MR, Costea I, Glod M, et al. Unusual malignant tumors of the thyroid gland. Chirurgia 2013; 108: 482–9.
Chung AY, Tran TB, Brumund KT, et al. Metastases to the thyroid: a review of the literature from the last decade. Thyroid 2012; 22: 258–68.
Moghaddam PA, Cornejo KM, Khan A. Metastatic carcinoma to the thyroid gland: a single institution 20-year experience and review of the literature. Endocr Pathol 2013; 24: 116–24.
Surov A, Machens A, Holzhausen HJ, et al. Radiological features of metastases to the thyroid. Acta Radiol 2016; 57: 444–50.
HooKim K, Gaitor J, Lin O, et al. Secondary tumors involving the thyroid gland: A multi-institutional analysis of 28 cases diagnosed on fine-needle aspiration. Diagn Cytopathol 2015; 43: 904–11.
Hegerova L, Griebeler ML, Reynolds JP, et al. Metastasis to the thyroid gland: report of a large series from the Mayo Clinic. Am J Clin Oncol 2015; 38: 338–42.
Plonczak AM, DiMarco AN, Dina R, et al. Breast cancer metastases to the thyroid gland — An uncommon sentinel for diffuse metastatic disease: A case report and literature review. J Med Case Rep 2017; 11: 288.
Russell JO, Yan K, Burkey B, et al. Nonthyroid metastasis to the thyroid gland: case series and review with observations by primary pathology. Otolaryngol Head Neck Surg 2016; 155: 961–8.
Cichon S, Anielski R, Konturek A, et al. Metastases to the thyroid gland: seventeen cases operated on in a single clinical center. Langenbecks Arch Surg 2006; 391: 581–7.
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