DELETION IN dbl DOMAIN OF bcr/abl GENE IN LEUKEMIA PATIENTS WITH Ph’ CHROMOSOME

Dybkov M.V., Telegeev G.D., Dubrovskaya A.N., Maliuta S.S.

In some leukemia patients with Ph' chromosome the presence of deletions in the dbl domain of hybrid bcr/abl gene was shown. The possible influence of such genetic alterations on peculiarities of disease course is discussed.