MATHEMATICAL ANALYSIS OF MORPHOLOGYCAL ALTERATIONS IN RADIORESISTANT TUMOR CELLS

Zinchenko V.A., Klyushin D.A., Baraboy V.A., Petunin Yu.I., Ganina K.P., Lavrenchuk G.I., Dudchenko T.M.

The system of quantitative parameters describing changes in tumor cells during development of their radioresistance in vitro was analysed. The index of significance for each of these descriptors was determined and the algorithm for differentiating radiosensitive and radioresistant tumor cells in populations is proposed on the basis of analysis of rat Guerin carcinoma cells.