INFLUENCE OF PEPTIDE COMPLEXES FROM KIDNEYS AND THYMUS ON DEXAMETHASONE- AND IONOPHORE-INDUCED APOPTOSIS IN THYMOCYTES AND PERIPHERAL BLOOD LYMPHOCYTES
On the basis of combined morphological, immunocytochemical and electrophoretic study the patterns of dexamethasone- and ionophore A23187-induced apoptosis in thymocytes and peripheral blood lymphocytes (PBL) were analyzed. PBL have been shown to be less susceptible to those agents than thymocytes. Incubation of dexamethasone- and ionophore-treated cells with peptide complexes from kidney or thymus resulted in decrease of their susceptibility to the apoptosis-inducing agents.
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