DIFFUSE LARGE B-CELL LYMPHOMA COMPLICATED BY BLEEDING FROM VARICOSE VEINS OF THE STOMACH AGAINST THE BACKGROUND OF SINISTRAL PORTAL HYPERTENSION. CASE STUDY AND LITERATURE REVIEW

Authors

  • D. RUDYK Bogomolets National Medical University, Department of Surgery Dentistry Faculty, Kyiv, Ukraine
  • M. TUTCHENKO Bogomolets National Medical University, Department of Surgery Dentistry Faculty, Kyiv, Ukraine
  • S. CHUB Bogomolets National Medical University, Department of Surgery Dentistry Faculty, Kyiv, Ukraine
  • M. BESEDINSKYI Bogomolets National Medical University, Department of Surgery Dentistry Faculty, Kyiv, Ukraine
  • A. LOVIN Taras Shevchenko National University, Educational and Scientific Center “Institute of Biology and Medicine”, Department of Surgery, Kyiv, Ukraine
  • I. AHAPCHENKО Kyiv City Clinical Hospital of Emergency Medical Aid, Kyiv, Ukraine

DOI:

https://doi.org/10.15407/exp-oncology.2025.01.102

Keywords:

diffuse large B-cell lymphoma, splenic vein thrombosis, sinistral portal hypertension, bleeding.

Abstract

Among 11,152 patients treated for complicated portal hypertension (PH) in the Kyiv Emergency Hospital in 2000— 2023, 394 (3.5%) had sinistral portal hypertension (SPH), the etiological factor of which in one patient (0.25% of SPH cases, 0.009% of all PH cases) was diffuse large B-cell lymphoma (DLBCL). We provide an example of successful surgical treatment of a patient with DLBCL that was complicated by the development of SPH with bleeding from varicose veins of the stomach. A peculiarity and difference between SPH and other forms of PH is not only the preserved patency of the portal vein and the normal gradient of portal pressure but also the preserved liver function.

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Published

11.07.2025

How to Cite

RUDYK, D., TUTCHENKO, M., CHUB, S., BESEDINSKYI, M., LOVIN, A., & AHAPCHENKО I. (2025). DIFFUSE LARGE B-CELL LYMPHOMA COMPLICATED BY BLEEDING FROM VARICOSE VEINS OF THE STOMACH AGAINST THE BACKGROUND OF SINISTRAL PORTAL HYPERTENSION. CASE STUDY AND LITERATURE REVIEW. Experimental Oncology, 47(1), 102–107. https://doi.org/10.15407/exp-oncology.2025.01.102