Cutaneous leiomyosarcoma: a clinical, dermoscopic, pathologic case study

Authors

  • V. De Giorgi Department of Dermatology, University of Florence, Florence 50100, Italy
  • F. Scarfì Department of Dermatology, University of Florence, Florence 50100, Italy
  • F. Silvestri Department of Dermatology, University of Florence, Florence 50100, Italy
  • P. Maida Department of Dermatology, University of Florence, Florence 50100, Italy
  • A. Gori Cancer Research “Attilia Pofferi” Foundation, Pistoia 51100, Italy
  • L. Trane Department of Dermatology, University of Florence, Florence 50100, Italy
  • D. Massi Department of Human Pathology and Oncology, University of Florence, Florence 50100,

DOI:

https://doi.org/10.32471/exp-oncology.2312-8852.vol-41-no-1.12816

Keywords:

cutaneous leiomyosarcoma, dermoscopic study, immunohistochemistry, pathology

Abstract

Summary. Cutaneous leiomyosarcoma is a rare malignant mesenchymal tumor of smooth muscle origin of unknown etiology. Leiomyosarcomas located on the skin include superficial leiomyosarcomas and metastatic leiomyosarcomas. Superficial leiomyosarcomas represent 7–10% of all cases of leiomyosarcoma and are subdivided into cutaneous and subcutaneous lesions based on skin location. We report a case of an 81-year-old woman who presented a slow growing tender single nodule on the left thigh and describe its clinical and dermoscopic features.

References

Massi D, Franchi A, Alos L, et. al. Primary cutaneous leiomyosarcoma: clinicopathological analysis of 36 cases. Histopathology 2010; 56: 251–62.

Starling J 3rd, Coldiron BM. Mohs micrographic surgery for the treatment of cutaneous leiomyosarcoma. J Am Acad Dermatol 2011; 64: 1119–22.

De Giorgi V, Sestini S, Massi D, et al. Superficial cutaneous leiomyosarcoma: a rare, misleading tumor. Am J Clin Dermatol 2008; 9: 185–7.

Torres T, Oliveira A, Sanches M, Selores M. Superficial cutaneous leiomyosarcoma of the face: report of three cases. J Dermatol 2011; 38: 373–6.

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Published

08.06.2023

How to Cite

Giorgi, V. D., Scarfì, F., Silvestri, F., Maida, P., Gori, A., Trane, L., & Massi, D. (2023). Cutaneous leiomyosarcoma: a clinical, dermoscopic, pathologic case study. Experimental Oncology, 41(1), 80–81. https://doi.org/10.32471/exp-oncology.2312-8852.vol-41-no-1.12816

Issue

Vol. 41 No. 1 (2019): Experimental Oncology

Section

Case report

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Copyright (c) 2023 Experimental Oncology

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