AUTOANTIBODIES AGAINST HUMAN BETA-DEFENSIN-2 IN THE BLOOD SERUM OF PATIENTS WITH VULVAL AND CERVICAL CANCER

Shnitsar V.M., Soldatkina M.A.1, Zinchenko I.I.2, Markeeva N.V.3, Rodnin N.V.4, Nespryadko S.V.5, Turchak O.V.6, Vinnitskaya A.B.6, Pogrebnoy P.V.1

Summary. The relevant levels of autoantibodies against hBD-2 in the blood serum of healthy donors, 13 patients with vulval cancer and 4 patients with cervical cancer have been studied by ELISA using recombinant hBD-2 as an antigen. In the serum of patients with vulval cancer of stages III–IV, the elevated levels of the anti-hBD-2-autoantibodies are revealed.

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