WORLD HEALTH ORGANIZATION CLASSIFICATION OF MALIGNANT LYMPHOMAS

Diebold J.

The historical background of classification of the neoplasms of lymphoid tissue has been presented beginning from the pioneer works of T. Hodgkin and R. Virchow till the up-to-date classification schemes developed by G. Rappaport and K. Lennert. The basic principles of the new WHO classification elaborated by the international group of pathologists have been analyzed in details with the emphasis on the criteria of delineating each nosologic entity taking into account the patterns of the growth (nodular or diffuse) as well as the origin of malignant cells defined upon the analysis of cytomorphological, immunophenotypic and molecular genetic features.

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