EFFICIENCY AND CHARACTERISTICS OF ANTI-TUMOR VACCINES BASED ON METABOLITES OF BACILLUS SUBTILIS 7025 CULTURED ON DIFFERENT MEDIA

Usach O.M., Tanasienko O.A., Yudina O.Y., Potebnya G.P., Savtsova Z.D.

Anti-tumor vaccines prepared from cells of Lewis carcinoma with the use of lectin containing fraction of the growth medium filtrate of B. subtilis 7025 cultured on meat-peptone broth or a semi-synthetic Gause medium optimized for lectin synthesis featured comparable levels of anti-metastatic activity and similar effects on the activity of effectors of anti-tumor resistance.

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